Find Family Hotels in St. Charles, MO

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Pick from 17 St. Charles Family Hotels and compare room rates, reviews, and availability. Most hotels are fully refundable.

Country Inn & Suites by Radisson, St. Charles, MO
Desk, laptop workspace, blackout drapes, iron/ironing board
Country Inn & Suites by Radisson, St. Charles, MO
2.5 star property
9.4 out of 10, Exceptional, (1000)
"Beautiful area "
The price is NT$3,218
NT$3,698 total
includes taxes & fees
Dec 1 - Dec 2
Country Inn & Suites by Radisson, St. Charles, MO
Embassy Suites by Hilton St. Louis St. Charles
Lobby
Embassy Suites by Hilton St. Louis St. Charles
3.5 star property
8.8 out of 10, Excellent, (1152)
"Stayed one night. "
The price is NT$4,112
NT$4,726 total
includes taxes & fees
Nov 25 - Nov 26
Embassy Suites by Hilton St. Louis St. Charles
Research Park Inn St Louis West – Chesterfield
Indoor pool
Research Park Inn St Louis West – Chesterfield
3.0 star property
5.8 out of 10, (1000)
"The hotel was under a major renovation as of Oct 2023. The rooms were dated, which is okay. The cleanliness of the room was acceptable. There wasn't much offered for the complimentary breakfast. I am sure this place will be a nice place to stay when finished. This hotel is a bargain compared to the surrounding area hotels."
Research Park Inn St Louis West – Chesterfield
Best Western Plus The Charles Hotel
Suite, 1 King Bed, Non Smoking, Refrigerator & Microwave | Premium bedding, pillowtop beds, in-room safe, desk
Best Western Plus The Charles Hotel
3.0 star property
8.0 out of 10, Very Good, (1001)
"Always a great stay here. I stay 2 times a year great staff. Great breakfast. "
The price is NT$3,077
NT$3,567 total
includes taxes & fees
Nov 26 - Nov 27
Best Western Plus The Charles Hotel
Hampton Inn St. Charles St. Peters
Exterior
Hampton Inn St. Charles St. Peters
2.5 star property
8.2 out of 10, Very Good, (1000)
"Clean, friendly staff, and priced right "
The price is NT$2,829
NT$3,251 total
includes taxes & fees
Nov 26 - Nov 27
Hampton Inn St. Charles St. Peters
Ameristar Casino Resort and Spa
Casino
Ameristar Casino Resort and Spa
4.5 star property
8.2 out of 10, Very Good, (1002)
"Great experience. However the room was a little warmer than what we're used to. We tried to cool it down, but was unsuccessful. "
The price is NT$5,487
NT$6,951 total
includes taxes & fees
Nov 19 - Nov 20
Ameristar Casino Resort and Spa
Sleep Inn & Suites
Lobby
Sleep Inn & Suites
2.5 star property
6.0 out of 10, (426)
"The room was comfortable. The shower was a bit wonky to turn on but we figured it out eventually. Beds were comfortable. The location was a bit noisy until traffic died down."
The price is NT$1,721
NT$1,977 total
includes taxes & fees
Dec 8 - Dec 9
Sleep Inn & Suites
Comfort Suites St Charles - St Louis
Property entrance
Comfort Suites St Charles - St Louis
2.5 star property
8.6 out of 10, Excellent, (786)
"Stay here frequently- dependable, good stay every time "
The price is NT$2,439
NT$2,804 total
includes taxes & fees
Nov 27 - Nov 28
Comfort Suites St Charles - St Louis
Baymont by Wyndham St. Charles
Lobby
Baymont by Wyndham St. Charles
2.5 star property
8.0 out of 10, Very Good, (965)
"My bed is clean and comfy! I always love that hotel use all white beddings and overall the room is clean and tidy. The area in St Charles is what makes me decide to stay here. Very safe and quiet. "
The price is NT$2,209
NT$2,538 total
includes taxes & fees
Nov 18 - Nov 19
Baymont by Wyndham St. Charles
Candlewood Suites St Louis St Charles, an IHG Hotel
Suite, 2 Bedrooms | Premium bedding, down comforters, pillowtop beds, in-room safe
Candlewood Suites St Louis St Charles, an IHG Hotel
2.5 star property
7.4 out of 10, Good, (670)
"Was clean, looked nice, and kind staff, they even brought us a pack n play for our son"
The price is NT$2,855
NT$3,281 total
includes taxes & fees
Nov 29 - Nov 30
Candlewood Suites St Louis St Charles, an IHG Hotel
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions

What's St. Charles like for family-friendly vacations?
The historic destination of St. Charles is a good choice if you’ve been thinking about a trip with your kids. The theaters and restaurants are just a few things that make this the ideal place for a family vacation. Arrange a flight into St. Louis Lambert Intl. Airport (STL), which is the closest airport, or St. Louis, MO (SUS-Spirit of St. Louis), which is located 11.7 mi (18.9 km) from the city center.
What's the best place to stay for a family vacation to St. Charles?
Country Inn & Suites by Radisson, St. Charles, MO is a hotel with an indoor pool and free parking, and it’s a top choice on Expedia for families. Other choices for your family trip include Country Inn & Suites by Radisson, St. Peters, MO and Drury Plaza Hotel St. Louis St. Charles.
How many hotels that welcome families can I expect to find in St. Charles?
Expedia has 9 family-friendly hotels and other accommodations in St. Charles.
When's the best time to book a family-friendly vacation in St. Charles?
The hottest months are usually July and August with an average temp of 75°F, while the coldest months are January and February with an average of 37°F. Average annual precipitation for St. Charles is 46 inches.
What's there to see and do with your family in St. Charles?
While you are visiting St. Charles, you might want to round up the kiddos and make time to see interesting attractions such as Fast Lane Classic Cars, Family Arena, and Lewis & Clark Boathouse and Nature Center. Make sure you have lots of time for activities like Weldon Spring Site Interpretive Center and Centene Community Ice Center.