East Prairie 2 Stars Hotels

Start date: Check-in selected.
To Date
End date: Check-out

  • Change your mind

    Book hotels with free cancellation

  • Treat yourself

    Sign in to save 10% or more on thousands of hotels
    Sign in

  • Be picky

    Search almost a million properties worldwide

Check availability on East Prairie 2 Star Hotels

Our top choices for East Prairie 2-star hotels

1 bedroom, desk, laptop workspace, blackout drapes
Days Inn and Suites by Wyndham Sikeston

Days Inn and Suites by Wyndham Sikeston

Days Inn and Suites by Wyndham Sikeston
2.0 star property
Sikeston
7.2 out of 10, Good, (1004)
"A great stay in every aspect. "
United States
Gertrude
The price is NT$1,962
NT$2,236 total
includes taxes & fees
Dec 16 - Dec 17
Days Inn and Suites by Wyndham Sikeston
Exterior
Hampton Inn Sikeston

Hampton Inn Sikeston

Hampton Inn Sikeston
2.5 star property
Sikeston
9.0 out of 10, Wonderful, (443)
"Room was clean and cozy, the check in-out staff were really nice and asked about our stay as well and the breakfast was a nice variety."
United States
Doncheial
The price is NT$2,970
NT$3,362 total
includes taxes & fees
Dec 21 - Dec 22
Hampton Inn Sikeston
Lobby
Sleep Inn at Discovery Park of America

Sleep Inn at Discovery Park of America

Sleep Inn at Discovery Park of America
2.5 star property
Union City
9.2 out of 10, Wonderful, (318)
"Wonderful breakfast, awesome room"
United States
Kimberly
The price is NT$2,519
NT$2,991 total
includes taxes & fees
Jan 4 - 2026/1/5
Sleep Inn at Discovery Park of America
Individually decorated, individually furnished, desk, blackout drapes
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)

Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
2.5 star property
Sikeston
8.4 out of 10, Very Good, (718)
"Stayed one night. Good rate for the Hotel "
United States
Paul
The price is NT$1,731
NT$1,973 total
includes taxes & fees
Dec 15 - Dec 16
Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
Free daily full breakfast
Best Western Plus Sikeston

Best Western Plus Sikeston

Best Western Plus Sikeston
2.5 star property
Sikeston
8.4 out of 10, Very Good, (1003)
"Easy parking , quiet and comfortable bed , we’ll stop again on our way back "
United States
joseph
The price is NT$2,227
NT$2,538 total
includes taxes & fees
Dec 21 - Dec 22
Best Western Plus Sikeston
Indoor pool, outdoor pool
Pear Tree Inn Sikeston

Pear Tree Inn Sikeston

Pear Tree Inn Sikeston
2.5 star property
Sikeston
9.4 out of 10, Exceptional, (1001)
"Everything was clean, staff was friendly "
United States
Matthew
The price is NT$2,339
NT$2,689 total
includes taxes & fees
Dec 21 - Dec 22
Pear Tree Inn Sikeston
Lobby
Hospitality House Union City I 69 / US 51

Hospitality House Union City I 69 / US 51

Hospitality House Union City I 69 / US 51
2.5 star property
Union City
6.8 out of 10, (367)
"Easy to check in.. Clean Room..Lots of food options near by.. "
United States
Pooran
The price is NT$1,697
NT$2,016 total
includes taxes & fees
Jan 12 - 2026/1/13
Hospitality House Union City I 69 / US 51
Property amenity
Fairfield Inn & Suites by Marriott Sikeston

Fairfield Inn & Suites by Marriott Sikeston

Fairfield Inn & Suites by Marriott Sikeston
2.5 star property
Sikeston
9.4 out of 10, Exceptional, (40)
"THE ROOM WAS SPOTLESS, CLEAN LOBBY, WARM AND LOT OF VARITY BREAKFAST, STAFF IS SO NICE."
United States
AHMAD
The price is NT$3,151
NT$3,567 total
includes taxes & fees
Dec 21 - Dec 22
Fairfield Inn & Suites by Marriott Sikeston
Exterior
Holiday Inn Express & Suites Sikeston Southwest by IHG

Holiday Inn Express & Suites Sikeston Southwest by IHG

Holiday Inn Express & Suites Sikeston Southwest by IHG
2.5 star property
Sikeston
8.6 out of 10, Excellent, (443)
"Staff was great. Hotel was clean. Great sleep. "
United States
Jeffrey
The price is NT$2,901
NT$3,285 total
includes taxes & fees
Dec 21 - Dec 22
Holiday Inn Express & Suites Sikeston Southwest by IHG
Laptop workspace, blackout drapes, free cribs/infant beds, free WiFi
Super 8 by Wyndham Charleston/Sikeston East MO

Super 8 by Wyndham Charleston/Sikeston East MO

Super 8 by Wyndham Charleston/Sikeston East MO
2.0 star property
Charleston
6.6 out of 10, (612)
"Staff was great! Room was nice. "
United States
Lana
The price is NT$1,937
NT$2,150 total
includes taxes & fees
Dec 15 - Dec 16
Super 8 by Wyndham Charleston/Sikeston East MO
Exterior
Holiday Inn Express & Suites Union City by IHG

Holiday Inn Express & Suites Union City by IHG

Holiday Inn Express & Suites Union City by IHG
2.5 star property
Union City
9.4 out of 10, Exceptional, (310)
"Rooms were spotless and comfortable. The bathroom had all the amenities. Great view. Awesome buffet breakfast to wake up to. "
United States
Rickey Smith
The price is NT$3,182
NT$3,778 total
includes taxes & fees
Dec 20 - Dec 21
Holiday Inn Express & Suites Union City by IHG
Terrace/patio
Hampton Inn Union City

Hampton Inn Union City

Hampton Inn Union City
2.5 star property
Union City
9.6 out of 10, Exceptional, (164)
"Clean room, nice breakfast"
United States
STUART
The price is NT$2,795
NT$3,319 total
includes taxes & fees
Dec 26 - Dec 27
Hampton Inn Union City
Free buffet breakfast
Quality Inn Union City US 51

Quality Inn Union City US 51

Quality Inn Union City US 51
2.5 star property
Union City
8.4 out of 10, Very Good, (485)
"The staff I interacted with were pleasant and helpful. Initially they had me in a 2nd floor room, but accommodated my asking for a first floor due to problems I was having with my knee and back. The bed was comfortable and overall the room was nice except for the bathroom shower, it had mold growing in it. Breakfast the next morning was ok."
United States
Rose
The price is NT$2,095
NT$2,487 total
includes taxes & fees
Jan 4 - 2026/1/5
Quality Inn Union City US 51
Premier Room, 1 Bedroom, Non Smoking | Desk, free WiFi, bed sheets
New Orleans Inn Portageville

New Orleans Inn Portageville

New Orleans Inn Portageville
2.5 star property
Portageville
8.0 out of 10, Very Good, (726)
"Quiet area and helpful staff. Glad we took a chance on this local hotel while traveling."
United States
Roger
New Orleans Inn Portageville
Lobby
Quality Inn Charleston - Sikeston

Quality Inn Charleston - Sikeston

Quality Inn Charleston - Sikeston
2.5 star property
Charleston
6.8 out of 10, (406)
"The staff was very friendly and accommodating "
United States
Arturo
The price is NT$2,049
NT$2,274 total
includes taxes & fees
Dec 21 - Dec 22
Quality Inn Charleston - Sikeston
Room, 1 Queen Bed, Non Smoking | Desk, laptop workspace, blackout drapes, free WiFi
Super 8 By Wyndham Marston

Super 8 By Wyndham Marston

Super 8 By Wyndham Marston
2.0 star property
Marston
7.8 out of 10, Good, (39)
"Great hotel, great staff"
United States
Dmitry
The price is NT$1,798
NT$2,054 total
includes taxes & fees
Dec 17 - Dec 18
Super 8 By Wyndham Marston
Room, 1 King Bed, Accessible, Non Smoking | Desk, laptop workspace, blackout drapes, free WiFi
Super 8 by Wyndham Sikeston/Miner Area

Super 8 by Wyndham Sikeston/Miner Area

Super 8 by Wyndham Sikeston/Miner Area
2.0 star property
Sikeston
6.6 out of 10, (563)
"ALL GREAT"
United States
NELSON
The price is NT$1,853
NT$2,112 total
includes taxes & fees
Dec 15 - Dec 16
Super 8 by Wyndham Sikeston/Miner Area
Standard Room, 2 Double Beds, Non Smoking | Blackout drapes, iron/ironing board, free WiFi, bed sheets
Reelfoot Lake Inn

Reelfoot Lake Inn

Reelfoot Lake Inn
2.0 star property
Tiptonville
7.2 out of 10, Good, (459)
"Nice and quiet but there were bugs in the room the fridge didn't keep things cold and the A/C didn't keep the room cool. Great place if you're a fisherman."
United States
Carla
The price is NT$2,175
NT$2,496 total
includes taxes & fees
Dec 15 - Dec 16
Reelfoot Lake Inn
Exterior
Comfort Inn & Suites Sikeston I-55

Comfort Inn & Suites Sikeston I-55

Comfort Inn & Suites Sikeston I-55
2.5 star property
Sikeston
8.4 out of 10, Very Good, (282)
"Room was clean, breakfast was very good. "
United States
Connie
The price is NT$2,625
NT$2,992 total
includes taxes & fees
Dec 21 - Dec 22
Comfort Inn & Suites Sikeston I-55
Lobby
Country Hearth Inn & Suites Union City

Country Hearth Inn & Suites Union City

Country Hearth Inn & Suites Union City
2.5 star property
Union City
8.6 out of 10, Excellent, (547)
"Clean rooms, helpful and polite staff"
United States
Jennifer
The price is NT$2,246
NT$2,667 total
includes taxes & fees
Dec 15 - Dec 16
Country Hearth Inn & Suites Union City
Save an average of 15% on thousands of hotels when you're signed in
Sign in
Sign up, it's free

Explore similar 3-star hotels

Many 3-star hotels have the same amenities as 2-star hotels. See all 3-star hotels in East Prairie.
Drury Inn & Suites Sikeston, MO

Drury Inn & Suites Sikeston, MO

2608 East Malone Ave, Miner Sikeston MO
The price is NT$2,807 per night from Dec 18 to Dec 19
NT$2,807
NT$3,227 total
Dec 18 - Dec 19
includes taxes & fees
9.4/10 Exceptional! (1,003 reviews)
Still don't see what you're looking for?
See all properties in East Prairie.
You can also use these popular filters to refine your search.
PoolSpaHot tubBreakfast includedWaterpark
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.

Learn more about East Prairie

Discover local heritage at the East Prairie Historical Museum, where artifacts tell the story of this Mississippi County town. Join the community for the annual Tour de Corn cycling event or explore nearby Big Oak Tree State Park for impressive ancient trees and wildlife viewing.

See all hotels in East Prairie
Bridge over Mississippi River, New Orleans in background

Top East Prairie Hotel Reviews

Super 8 by Wyndham Sikeston/Miner Area

Super 8 by Wyndham Sikeston/Miner Area

10/10 Excellent
" Clean rooms , quiet , excellent hotel staff."
James 1-night trip
Posted 4 days ago
Super 8 by Wyndham Sikeston/Miner Area

Explore a world of travel with Expedia