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We have found 78 East Prairie Hotels
- Days Inn and Suites by Wyndham Sikeston
- Pear Tree Inn Sikeston
- Drury Inn & Suites Sikeston, MO
- Best Western Plus Sikeston
- New Orleans Inn Portageville
- Holiday Inn Express & Suites Union City by IHG
- Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
- Hospitality House Union City US 51
- Holiday Inn Express & Suites Sikeston Southwest by IHG
- Sleep Inn
- Hampton Inn Sikeston
- Super 8 By Wyndham Marston
- Hampton Inn Union City
- Country Hearth Inn & Suites Union City
- Super 8 by Wyndham Charleston/Sikeston East MO
- Country Yard Inn and Suite
- Comfort Inn & Suites Sikeston I-55
- Travel Inn
- Super 8 by Wyndham Sikeston/Miner Area
- Quality Inn Charleston - Sikeston
- Quality Inn Union City US 51
- Reelfoot Lake Inn
- TownePlace Suites by Marriott Sikeston
- Quality Inn Cairo I-57
- Rosewood Inn By OYO Union City I-69
- MainStay Suites Union City, TN
- Eagle Inn Charleston
- Fairfield by Marriott Inn & Suites Sikeston
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