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Find hotels in South Main, Houston from NT$1,668

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Check prices for these dates

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Mar 4 - Mar 5
Tomorrow
Mar 5 - Mar 6
This weekend
Mar 7 - Mar 9
Next weekend
Mar 14 - Mar 16

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Discover 6,387 South Main hotels and places to stay, with room rates, reviews, and availability. Most hotels are fully refundable.

Comfort Suites near Texas Medical Center - NRG Stadium
Lobby

Comfort Suites near Texas Medical Center - NRG Stadium

2.5 star property
8.6 out of 10, Excellent, (788)
"Always stay here for price and convenience "
The price is NT$3,406
NT$3,985 total
includes taxes & fees
Mar 27 - Mar 28
Comfort Suites near Texas Medical Center - NRG Stadium
Wyndham Houston near NRG Park/Medical Center
View from property

Wyndham Houston near NRG Park/Medical Center

3.5 star property
7.2 out of 10, Good, (1012)
"Odd shower, kept getting water everywhere as it was a handicap bathroom (despite us not being handicapped) so kept running out of towels and the floor was always wet"
The price is NT$4,574
NT$5,351 total
includes taxes & fees
Mar 24 - Mar 25
Wyndham Houston near NRG Park/Medical Center
Candlewood Suites Houston Medical Center by IHG
Exterior

Candlewood Suites Houston Medical Center by IHG

2.5 star property
7.6 out of 10, Good, (738)
"Good overall, there was no tv remote, no trash can in kitchen and chair was not clean. Some red water came out from bathtub faucet when opened first time. Overall good. "
The price is NT$2,435
NT$2,849 total
includes taxes & fees
Mar 28 - Mar 29
Candlewood Suites Houston Medical Center by IHG
Quality Inn & Suites NRG Park - Medical Center
Hypo-allergenic bedding, in-room safe, individually decorated

Quality Inn & Suites NRG Park - Medical Center

2.5 star property
6.6 out of 10, (1001)
" It at this time"
The price is NT$1,976
NT$2,312 total
includes taxes & fees
Apr 3 - Apr 4
Quality Inn & Suites NRG Park - Medical Center
Wingate Houston near NRG Park/Medical Center
Room, 2 Double Beds, Non Smoking | Desk, laptop workspace, blackout drapes, iron/ironing board

Wingate Houston near NRG Park/Medical Center

3.0 star property
6.8 out of 10, (817)
"Good"
The price is NT$3,821
NT$4,470 total
includes taxes & fees
Apr 4 - Apr 5
Wingate Houston near NRG Park/Medical Center
OYO Hotel Houston Tx Medical Center Nrg Stadium
Lobby

OYO Hotel Houston Tx Medical Center Nrg Stadium

2.5 star property
3.8 out of 10, (415)
"this was the worst hotel ive ever stayed in. roaches and gnats"
The price is NT$1,668
NT$2,149 total
includes taxes & fees
Mar 17 - Mar 18
OYO Hotel Houston Tx Medical Center Nrg Stadium
La Quinta Inn & Suites by Wyndham Houston East at Sheldon Rd
Pillowtop beds, desk, iron/ironing board, free WiFi

La Quinta Inn & Suites by Wyndham Houston East at Sheldon Rd

3.5 star property
9.2 out of 10, Wonderful, (906)
"Amazing stay and clean rooms with comfy beds. Staff was super nice. "
The price is NT$2,294
NT$2,638 total
includes taxes & fees
Mar 30 - Mar 31
La Quinta Inn & Suites by Wyndham Houston East at Sheldon Rd
Sonesta Simply Suites Houston – NASA Clear Lake
Fridge, microwave, stovetop, dishwasher

Sonesta Simply Suites Houston – NASA Clear Lake

2.5 star property
8.2 out of 10, Very Good, (848)
"Lost spelling of name unfortunately but believe was Rameysha close to that, very sweet, knowledgeable and assisted me with some personal paperwork I needed. Went out her way to make us feel comfortable. Great customer service. Clean rooms, enjoyed our weekend stay. We will be back. "
The price is NT$2,238
NT$2,618 total
includes taxes & fees
Apr 3 - Apr 4
Sonesta Simply Suites Houston – NASA Clear Lake
SureStay Hotel by Best Western Deer Park
In-room safe, individually furnished, desk, laptop workspace

SureStay Hotel by Best Western Deer Park

2.5 star property
8.6 out of 10, Excellent, (207)
"Stuff"
The price is NT$2,369
NT$2,772 total
includes taxes & fees
Mar 31 - Apr 1
SureStay Hotel by Best Western Deer Park
stayAPT Suites Houston NASA Clear Lake
Exterior

stayAPT Suites Houston NASA Clear Lake

2.5 star property
9.4 out of 10, Exceptional, (271)
"There was some leftover food in our fridge. Freezer was a bit nasty. There was no coffee pot for the coffee maker. Other than that everything was fine! "
The price is NT$3,290
NT$3,850 total
includes taxes & fees
Mar 11 - Mar 12
stayAPT Suites Houston NASA Clear Lake
La Quinta Inn & Suites by Wyndham Houston/Clear Lake-NASA
Suite, 2 Queen Beds, Non Smoking | Premium bedding, desk, iron/ironing board, free cribs/infant beds

La Quinta Inn & Suites by Wyndham Houston/Clear Lake-NASA

2.5 star property
7.8 out of 10, Good, (1005)
"Need more parking."
The price is NT$2,266
NT$2,651 total
includes taxes & fees
Mar 30 - Mar 31
La Quinta Inn & Suites by Wyndham Houston/Clear Lake-NASA
Best Western Webster Hotel, Nasa
Seasonal outdoor pool, pool umbrellas, sun loungers

Best Western Webster Hotel, Nasa

2.5 star property
7.6 out of 10, Good, (1003)
"The stay was great, Angel at the front desk was amazing and so helpful!!! "
The price is NT$2,063
NT$2,414 total
includes taxes & fees
Apr 1 - Apr 2
Best Western Webster Hotel, Nasa
La Quinta Inn & Suites by Wyndham Houston Channelview
Exterior

La Quinta Inn & Suites by Wyndham Houston Channelview

3.5 star property
8.6 out of 10, Excellent, (696)
"Great customer service, fast check in, very secure and felt safe. "
The price is NT$2,752
NT$3,220 total
includes taxes & fees
Mar 30 - Mar 31
La Quinta Inn & Suites by Wyndham Houston Channelview
Holiday Inn Express & Suites Houston East - Beltway 8 by IHG
Exterior

Holiday Inn Express & Suites Houston East - Beltway 8 by IHG

2.5 star property
8.4 out of 10, Very Good, (360)
"Definitely nice and clean "
The price is NT$2,665
NT$3,118 total
includes taxes & fees
Mar 16 - Mar 17
Holiday Inn Express & Suites Houston East - Beltway 8 by IHG
Palace Inn Blue Houston East Beltway 8
Reception

Palace Inn Blue Houston East Beltway 8

2.5 star property
9.0 out of 10, Wonderful, (249)
"Great"
The price is NT$2,517
NT$2,895 total
includes taxes & fees
Mar 12 - Mar 13
Palace Inn Blue Houston East Beltway 8
La Quinta Inn & Suites by Wyndham Pasadena North
Lobby

La Quinta Inn & Suites by Wyndham Pasadena North

2.5 star property
7.8 out of 10, Good, (536)
"Everything was clean..good customer service "
The price is NT$2,738
NT$3,203 total
includes taxes & fees
Apr 2 - Apr 3
La Quinta Inn & Suites by Wyndham Pasadena North
Bluestar Inn
Individually furnished, desk, iron/ironing board, free WiFi

Bluestar Inn

2.5 star property
9.0 out of 10, Wonderful, (199)
"Amazing i love it i will be back soon"
The price is NT$2,270
NT$2,656 total
includes taxes & fees
Mar 12 - Mar 13
Bluestar Inn
Best Western Plus Heritage Inn
Reception

Best Western Plus Heritage Inn

3.0 star property
8.0 out of 10, Very Good, (594)
"Convenient and accessible to major interstate. Dining nearby. Felt safe. "
The price is NT$2,577
NT$3,015 total
includes taxes & fees
Mar 12 - Mar 13
Best Western Plus Heritage Inn
Woodspring Suites South Houston Hobby
Suite, 1 King Bed, Non Smoking | Individually furnished, desk, laptop workspace, bed sheets

Woodspring Suites South Houston Hobby

2.5 star property
7.8 out of 10, Good, (151)
"Xo"
The price is NT$1,941
NT$2,271 total
includes taxes & fees
Mar 9 - Mar 10
Woodspring Suites South Houston Hobby
Palace Inn Blue Edgebrook
Free daily on-the-go breakfast

Palace Inn Blue Edgebrook

2.5 star property
9.0 out of 10, Wonderful, (79)
"Only observation is the room really needed to have lamps. The overhead lights, even the ones that are above, the bed are very very bright."
The price is NT$2,876
NT$3,466 total
includes taxes & fees
Mar 9 - Mar 10
Palace Inn Blue Edgebrook
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions

What is South Main like?

You'll be sure to have fun visiting Houston's South Main neighborhood. Consider a visit to NRG Park as part of your South Main travel plans.

Where is the best hotel for a stay in South Main?

Based on Expedia customer reviews, Comfort Suites near Texas Medical Center - NRG Stadium is the highest ranked property in South Main. This hotel is a short 9-minute walk from NRG Stadium, and it offers free breakfast and free parking. Other top choices in the neighborhood include Candlewood Suites Houston Medical Center by IHG and Wyndham Houston near NRG Park/Medical Center.

How many hotels will I be able to find in South Main?

If you're searching for places to stay in Houston, Expedia has something to meet your needs with 64 South Main hotels and other accommodations to choose from.

If I need to cancel my hotel reservation in South Main, will I receive a refund?

Yes, the majority of hotel bookings are refundable provided that you cancel before the accommodation's cancellation deadline, which is often 24 or 48 hours before your scheduled arrival. If you booked a non-refundable reservation, you might be able to still cancel and be given a refund within a 24-hour period of your booking. Enter dates in and click on "Search", then use the filter option "fully refundable" to get the best options available in South Main.

Where can I learn more about changing or cancelling my trip to South Main?

For more details about changing or cancelling your trip to South Main, head over to our customer service page.

What can I see and do in this Houston neighborhood?

NRG Park is an attraction you might want to check out while you're in South Main. While you're out sightseeing in Houston, be sure to visit other sights like NRG Stadium or NRG Arena.

How can I get around South Main and the greater Houston area?

Ready to get out and explore the city? Fannin South Station is the closest metro station.