Independent Otay Mesa hotels
- Plan, book, stay with confidence
Be picky
Search almost a million properties worldwide
Change your mind
Book hotels with free cancellation
Check prices for these dates
Compare rooms and suites by Independent in Otay Mesa with rates, reviews, and availability. Most hotels are fully refundable.

The Bristol Hotel San Diego
The Bristol Hotel San Diego
8.4 out of 10, Very Good, (1266)
The price is NT$5,221
NT$5,884 total
includes taxes & fees
Mar 3 - Mar 4

Bay Club Hotel & Marina
Bay Club Hotel & Marina
9.0 out of 10, Wonderful, (2444)
The price is NT$4,575
NT$5,156 total
includes taxes & fees
Mar 23 - Mar 24

The Dana on Mission Bay
The Dana on Mission Bay
8.8 out of 10, Excellent, (3194)
The price is NT$5,543
NT$6,247 total
includes taxes & fees
Mar 2 - Mar 3

Lafayette Hotel & Club
Lafayette Hotel & Club
9.0 out of 10, Wonderful, (626)
The price is NT$6,756
NT$7,601 total
includes taxes & fees
Mar 3 - Mar 4

Paradise Point Resort & Spa
Paradise Point Resort & Spa
8.6 out of 10, Excellent, (2090)
The price is NT$6,888
NT$9,391 total
includes taxes & fees
Feb 28 - Mar 1

Legacy Resort Hotel & Spa
Legacy Resort Hotel & Spa
9.2 out of 10, Wonderful, (2874)
The price is NT$5,422
NT$6,110 total
includes taxes & fees
Mar 4 - Mar 5

Margaritaville Hotel San Diego Gaslamp Quarter
Margaritaville Hotel San Diego Gaslamp Quarter
9.0 out of 10, Wonderful, (791)
The price is NT$6,943
NT$9,118 total
includes taxes & fees
Mar 15 - Mar 16

Heritage Inn La Mesa
Heritage Inn La Mesa
6.2 out of 10, (1006)
The price is NT$2,251
NT$2,482 total
includes taxes & fees
Mar 3 - Mar 4
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
Save an average of 15% on thousands of hotels when you're signed in
Find out more about Otay Mesa
Find out more about Otay Mesa
Otay Mesa hotels information
Number of reviews | 17,163 |
---|---|
Accommodation | 4,547 hotels |
Lowest Price | NT$2,251 |
Highest Price | NT$6,943 |
Recent reviews of Otay Mesa hotels
Recent reviews of Otay Mesa hotels

Wyndham San Diego Bayside
5/5 Excellent
"Convenient location and quiet."
A verified traveler stayed at Wyndham San Diego Bayside
Posted 6 hours ago
Explore a world of travel with Expedia
Explore a world of travel with Expedia
Otay Mesa Hotels by Brand
Hotels in Otay Mesa Neighborhoods
Hotels near popular San Diego Attractions
- Hotels near San Diego Zoo
- Hotels near San Diego Convention Center
- Hotels near Mission Bay
- Hotels near San Ysidro Border Crossing
- Hotels near Balboa Park
- Hotels near Mission Beach
- Hotels near Petco Park
- Hotels near San Diego State University
- Hotels near Hotel Circle
- Hotels near Marine Corps Recruit Depot
More Hotel Options in Otay Mesa
- Beach Hotels in Otay Mesa
- Business Hotels in Otay Mesa
- Casinos in Otay Mesa
- Cheap Hotels in Otay Mesa
- Family Hotels in Otay Mesa
- Golf Hotels in Otay Mesa
- Historic Hotels in Otay Mesa
- Hotels with Free Parking in Otay Mesa
- Hotels with Hot Tubs in Otay Mesa
- Hotels with WiFi in Otay Mesa
- Hotels with a Pool in Otay Mesa
- Hotels with smoking rooms in Otay Mesa
- Luxury Hotels in Otay Mesa
- Resorts & Hotels with Spas in Otay Mesa
- Shopping Hotels in Otay Mesa
- Winery Hotels in Otay Mesa
More Accommodation Types in Otay Mesa
Explore more hotels
- Kings Inn San Diego
- The Horton Grand, Downtown/Gaslamp Quarter
- Wyndham Garden San Diego Near SeaWorld
- Paradise Point Resort & Spa
- Manchester Grand Hyatt San Diego
- The Sofia Hotel
- Best Western Plus Marina Gateway Hotel
- San Diego Mission Bay Resort
- Legacy Resort Hotel & Spa
- Marriott Marquis San Diego Marina
- Days Inn by Wyndham San Diego Hotel Circle
- Best Western Inn & Suites San Diego – Zoo/SeaWorld Area
- Alma San Diego Downtown, a Tribute Portfolio Hotel
- Pendry San Diego
- Bahia Resort Hotel
- The Westin San Diego Bayview
- The Guild Hotel, San Diego, A Tribute Portfolio Hotel by Marriott
More ways to book
Expedia's Latest Trends
Hotels
Flights
Flights to TibetFlights from Taoyuan City (TPE) to Jiujiang (JIU)China Airlines Taoyuan City (TPE) to Takamatsu (TAK) flightsFlights from Taoyuan City (TPE) to Seville (SVQ)Flights from Taoyuan City (TPE) to Malay (MPH)Flights from Taoyuan City (TPE) to Tawau (TWU)Flights from Taoyuan City (TPE) to Winnipeg (YWG)
Packages