Find Resorts & Hotels with Spas in Hannibal, MO

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Pick from 10 Hannibal Resorts & Hotels with Spas and compare room rates, reviews, and availability. Most hotels are fully refundable.

Sleep Inn & Suites
Exterior
Sleep Inn & Suites
2.5 star property
9.6 out of 10, Exceptional, (1004)
"Very nice and well kept, front desk was very friendly and right there to help. "
The price is NT$3,293
NT$3,782 total
includes taxes & fees
Dec 1 - Dec 2
Sleep Inn & Suites
Comfort Inn & Suites - Hannibal
Indoor pool, sun loungers
Comfort Inn & Suites - Hannibal
2.5 star property
7.6 out of 10, Good, (525)
"Room was clean. Plenty of space."
The price is NT$2,554
NT$3,030 total
includes taxes & fees
Nov 24 - Nov 25
Comfort Inn & Suites - Hannibal
Motel 6 Hannibal, MO
Lobby sitting area
Motel 6 Hannibal, MO
2.0 star property
7.4 out of 10, Good, (1003)
"The room was clean, had microwave and refrigerator. No coffee maker. TV was very limited, but we found enough to watch. Barebones place, but clean and a value for money. We just needed a place to sleep."
The price is NT$1,786
NT$2,052 total
includes taxes & fees
Nov 10 - Nov 11
Motel 6 Hannibal, MO
Howard Johnson BY Wyndham Hannibal
Lobby sitting area
Howard Johnson BY Wyndham Hannibal
2.5 star property
7.0 out of 10, Good, (98)
"Hv"
The price is NT$1,782
NT$2,049 total
includes taxes & fees
Nov 26 - Nov 27
Howard Johnson BY Wyndham Hannibal
Baymont by Wyndham Hannibal
Desk, laptop workspace, iron/ironing board, free WiFi
Baymont by Wyndham Hannibal
2.5 star property
6.0 out of 10, (593)
"This property had mixed reviews but I bit the bullet and booked it. I was soooo glad I did. It was clean and the staff very friendly and nice. The breakfast was on point and was a great place to stay. I won't have an issue booking it again. Thank you for such a great stay"
The price is NT$1,790
NT$2,058 total
includes taxes & fees
Dec 1 - Dec 2
Baymont by Wyndham Hannibal
Days Inn by Wyndham Hannibal
Seasonal outdoor pool
Days Inn by Wyndham Hannibal
2.0 star property
7.2 out of 10, Good, (129)
"Nice staff, store and gas next door."
The price is NT$2,154
NT$2,474 total
includes taxes & fees
Nov 29 - Nov 30
Days Inn by Wyndham Hannibal
Super 8 by Wyndham Hannibal
Exterior
Super 8 by Wyndham Hannibal
2.0 star property
7.2 out of 10, Good, (1004)
"Great!"
The price is NT$1,844
NT$2,118 total
includes taxes & fees
Dec 1 - Dec 2
Super 8 by Wyndham Hannibal
Best Western On The River
Indoor pool, seasonal outdoor pool, pool umbrellas, sun loungers
Best Western On The River
2.5 star property
8.6 out of 10, Excellent, (1010)
"Grace is the best CS rep. we've ever met at the front desk. Didn't get his name but the breakfast cook is exceptional. His scrambled eggs were incredible and we have never had eggs this light, airy, and tasty, ever, in a breakfast buffet. "
The price is NT$3,414
NT$3,920 total
includes taxes & fees
Nov 6 - Nov 7
Best Western On The River
Garth Woodside Mansion B&B
Exterior
Garth Woodside Mansion B&B
3.5 star property
9.6 out of 10, Exceptional, (16)
"Quiet and isolated in a wooded area."
Garth Woodside Mansion B&B
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions

Looking to vacation at a spa hotel in Hannibal?
Forget the stress of everyday life and book yourself a hotel with a spa. Travelers recommend the gourmet restaurants in Hannibal. Enjoy the shopping and riverfront during your vacation. Spa hotels are a great way to break out of your routine and add a layer of luxury to your vacation.
What is the best spa hotel in Hannibal?
Comfort Inn & Suites - Hannibal is a top spa hotel featuring a 24-hour fitness center and an indoor pool. Kick back and relax in the spa tub.
How many spa hotels are there in Hannibal?
Among Expedia’s 50 accommodation options in Hannibal, there is 1 spa hotel.
What's there to see and do in Hannibal?
Take in the sights and attractions that Hannibal offers with a visit to Mark Twain Boyhood Home and Museum, Mark Twain Cave and Cameron Cave, and Mark Twain Cave. If you have a little extra time during your trip, you might want to check out Mississippi River and Big River Train Town.
What is a Hannibal spa hotel?
Spa hotels in Hannibal provide lodging and have an on-site spa offering services such as couples massages and beauty treatments. Some also offer in-room treatments. Spa hotels are great for rest, rejuvenation, and relaxation.