Find Business Hotels in Downtown San Diego, CA

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Check availability on Downtown San Diego Business Hotels

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Compare Downtown San Diego Business Hotels room rates, reviews, and availability. Most hotels are fully refundable.

The Sofia Hotel

3.5 star property
8.2 out of 10, Very Good, (1617)
"This was my second stay at this property. The staff and l location are fantastic. On check-in, I did experience a foul odour of urine in my room. I reported this to reception and was provided a new room. My first stay was perfect, this time however; the odour in the room, and tiredness of the replacement room were a bit of a shame. The replacement room had a toilet seat that was not fixed to the toilet, the sink had a large crack in it, and the sink tap was wobbly and loose. Other than that, it...
The price is NT$5,078
NT$6,466 total
includes taxes & fees
Apr 10 - Apr 11
The Sofia Hotel

Wyndham San Diego Bayside

4.0 star property
8.2 out of 10, Very Good, (6550)
"The property was nice and well kept up, staff was accommodating. The only negative feature was the shower didn’t drain well. "
The price is NT$5,040
NT$5,679 total
includes taxes & fees
Apr 18 - Apr 19
Wyndham San Diego Bayside

The Horton Grand, Downtown/Gaslamp Quarter

3.5 star property
8.8 out of 10, Excellent, (2627)
"My stay at the historic Horton Grand in San Diego was unmatched in excellence. Located in the heart of the Gaslamp Quarter, it is an easy walk to Petco Park, the Children's Museum, the USS Midway, and many dining and nightlife options. It is staffed by very friendly and helpful people who went out of their way to make our stay as comfortable as possible. Our room was in the fourth floor and overlooked the courtyard whose trees were illuminated nightly. This hotel includes many antique...
The price is NT$4,841
NT$6,351 total
includes taxes & fees
Apr 13 - Apr 14
The Horton Grand, Downtown/Gaslamp Quarter

Manchester Grand Hyatt San Diego

4.0 star property
9.0 out of 10, Wonderful, (3357)
"Awesome view wonderful staff!!"
The price is NT$6,260
NT$8,629 total
includes taxes & fees
Apr 17 - Apr 18
Manchester Grand Hyatt San Diego

Urban Boutique Hotel

3.0 star property
8.6 out of 10, Excellent, (1413)
"it was a great place to stay, lots of food options and walk 30 min to downtown, close to public transport, the room was clean enough, not to my expectation though, but staff are great and welcoming "
The price is NT$4,740
NT$5,238 total
includes taxes & fees
Apr 13 - Apr 14
Urban Boutique Hotel

Hilton San Diego Bayfront

4.0 star property
8.4 out of 10, Very Good, (1810)
"Location is great with nice views over the water. Well maintained property. Staff was helpful. Breakfast at Hudson is excellent. "
The price is NT$3,574
NT$5,606 total
includes taxes & fees
Apr 20 - Apr 21
Hilton San Diego Bayfront

Hard Rock Hotel San Diego

4.0 star property
8.8 out of 10, Excellent, (2943)
"The property itself is extremely clean "
The price is NT$5,538
NT$7,734 total
includes taxes & fees
Apr 18 - Apr 19
Hard Rock Hotel San Diego

Comfort Inn Gaslamp Convention Center

2.5 star property
7.8 out of 10, Good, (1207)
"Really helpful and obliging staff; greeted us each time we returned and made our stay all the better. Good location in a funky neighbourhood."
The price is NT$3,350
NT$3,776 total
includes taxes & fees
Apr 21 - Apr 22
Comfort Inn Gaslamp Convention Center

Embassy Suites by Hilton San Diego Bay Downtown

4.0 star property
8.8 out of 10, Excellent, (1331)
"I travel alot and this was one of my favorite places to stay! Great free breakfast every morning, pool, clean, great staff, wonderful location. 10/10 recommended! "
The price is NT$6,507
NT$8,267 total
includes taxes & fees
Apr 9 - Apr 10
Embassy Suites by Hilton San Diego Bay Downtown

Sheraton San Diego Resort

4.0 star property
8.0 out of 10, Very Good, (2953)
"i left medication in the frig of my room. i spoke to Michael in security and he recovered the prescription in my room. he made everything easy for me to have it shipped out. he's my hero!! i thank him so so much.he really showed that he cared."
The price is NT$5,035
NT$7,018 total
includes taxes & fees
Apr 20 - Apr 21
Sheraton San Diego Resort
Lowest nightly price found within the past 24 hours based on a 1 night stay for 2 adults. Prices and availability subject to change. Additional terms may apply.
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Frequently asked questions

Why book your business-friendly hotel in Downtown San Diego with Expedia?
With amenities like conference rooms, 24-hour front desk support and free WiFi, our business-friendly properties come with all you’ll need to get the job done — and then kick back! Enter your destination and preferred travel dates and we’ll help you organize the rest.
How can I find cheap business-friendly hotels in Downtown San Diego?
Click on the “business friendly” filter, listed under the “traveler experience” heading, to find cheap business-friendly hotels in Downtown San Diego. Then fine-tune your search by your budget and preferred hotel star rating. Looking for stays outside the city center is another easy way to save.