Find All Southeast Missouri Hotels
We have found 531 Southeast Missouri Hotels
- Motel 6 Poplar Bluff, MO
- Baymont Inn and Suites by Wyndham Farmington, MO
- Holiday Inn Express Hotel & Suites Cape Girardeau I-55, an IHG Hotel
- La Quinta Inn & Suites by Wyndham Jackson/Cape Girardeau
- Drury Inn & Suites Cape Girardeau
- Drury Inn & Suites Sikeston, MO
- Pear Tree Inn Cape Girardeau West
- Pear Tree Inn Sikeston
- Drury Plaza Hotel Cape Girardeau Conference Center
- Pear Tree Inn Cape Girardeau Near the Medical Center
- Days Inn and Suites by Wyndham Sikeston
- Drury Inn & Suites Hayti Caruthersville
- La Quinta Inn & Suites by Wyndham Festus - St. Louis South
- Candlewood Suites Cape Girardeau, an IHG Hotel
- Courtyard by Marriott Cape Girardeau Downtown
- Fairfield Inn & Suites by Marriott Poplar Bluff
- New Orleans Inn Portageville
- Hampton Inn Poplar Bluff
- Holiday Inn Express & Suites Perryville, an IHG Hotel
- Quality Inn
- Hampton Inn Cape Girardeau I 55 East
- Holiday Inn Express Hotel & Suites FESTUS - SOUTH ST. LOUIS, an IHG Hotel
- Drury Inn & Suites Poplar Bluff
- Best Western Plus Sikeston
- Super 8 by Wyndham Perryville
- Holiday Inn Poplar Bluff, an IHG Hotel
- Comfort Inn Festus - St Louis South
- Travel Inn & Suites - Sikeston/Miner (i-55 Exit-67)
- Super 8 by Wyndham Poplar Bluff Missouri
- Drury Inn & Suites Jackson MO
- Town House Inn
- Comfort Suites Jackson-Cape Girardeau
- Comfort Inn Poplar Bluff North
- Hampton Inn Sikeston
- Quality Inn Farmington
- Super 8 by Wyndham Bonne Terre
- Super 8 by Wyndham Farmington
- Dexter Inn
- Echo Bluff State Park
- Super 8 by Wyndham Sikeston/Miner Area
- Holiday Inn Express & Suites Sikeston Southwest, an IHG Hotel
- Days Inn by Wyndham Perryville
- Super 8 by Wyndham Potosi
- Honeysuckle Inn - Mountain View
- Bullwinkles Rustic Lodge
- Super 8 by Wyndham Charleston/Sikeston East MO
- Econo Lodge Dexter
- Town House Inn Cape Giradreau
- Quality Inn Hayti North
- Hampton Inn Farmington
- Madison Inn Lodge
- Econo Lodge
- Holiday Inn Express & Suites Farmington, an IHG Hotel
- Super 8 by Wyndham Kennett
- Quality Inn Charleston - Sikeston
- Crown Pointe Lodge, BW Signature Collection
- Travelodge by Wyndham Dexter
- Current River Inn
- Comfort Inn & Suites Sikeston I-55
- Hickory House Inn
- Shepherd Mountain Inn
- Quality Inn
- Travel Inn
- Fort Davidson Hotel
- Wilderness Lodge
- Triangle Inn Motel
- Eagle Inn Charleston
- Rosener's Inn and banquet center
- Super 8 by Wyndham Pevely
- Eagle's Landing River Resort
Let Expedia take you to the best Hotels in Southeast Missouri. You'll find the largest selection of hotel deals, discount prices, and cheap hotel rates on reservations anywhere in the world. Expedia, the leader in world travel, gives you customer reviews, maps, and the best selection of hotels near landmarks and attractions.